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  • Writer's pictureKelly Alica Liman

Top 51 Angel Investor Groups in the United States of America

For anyone looking to start a business, the United States offers nothing short of a paradise of opportunities. The country has long been renowned as the prime birthplace of innovation, evidenced by its 70% share of the North American ecosystem, which includes Silicon Valley, New York City, Boston, and Los Angeles. The startup ecosystem in the United States provides significant opportunities for entrepreneurs as well as investors. In this article, we have collected a comprehensive list of Angel Investors and Angel Investment Networks in the USA, so you may find the right partner to grow your business.


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Why Should You Raise Funds with Angel Investors in the United States of America?


The United States remains to be the dominant market for angel investment, with the number of active angel investors continuing to expand. The Small Business Administration estimates that there are currently over 250,000 active angel investors in the country who support over 30,000 firms per year. If you're in the early days of building your startup, here are 3 main reasons why you should raise capital with angel investors in the United States:


  1. Access to Funding: Angel investors may provide the capital startups need to build their businesses without the limitation of typical bank loans. With the volatility of the present market, several financial institutions have tightened lending standards that make it increasingly difficult for new firms and entrepreneurs to secure. As such, angel investments are a great alternative for early-stage firms as angel investors are often willing to offer more flexible terms than traditional sources of funding. According to the ACA Angel Funders Report, each angel group invests approximately $4.7 million per year across various companies, a 15% increase from investments made in 2021.

  2. Mentorship and Knowledge: Angel investors are usually successful entrepreneurs with numerous experiences in building various businesses. Though some may take a backseat in the management of startups, there are also angels who will want a "hands-on" approach to the management of the firms. These angels may get directly involved in the business and offer their mentorship, guidance, and expertise.

  3. Industry Connection: As previously mentioned, angel investors are usually seasoned entrepreneurs who may have a large network of industry contacts. They would usually assist businesses with an introduction to their network and can help you gain credibility and trust from partners, other investors, and potential customers.


It's important to note that taking funds from angel investors has its own disadvantages, such as potentially giving up some control over decision-making and diluting of equity. As such, it is critical for startups to thoroughly analyze all of their funding options and select the one that best meets their specific requirements and ambitions.





How Can You Meet Angel Investors in the United States of America?


There are various avenues where you can find and meet angel investors in the United States:

  1. Online Platforms: There are now platforms such as Angel Investment Network US and US Investment Network that allow you to post your startup projects and present your company to potential investors. These platforms also have a search function where you can browse through their angel investor members to find one that is suitable for you. This article also contains a number of angel investor groups across the USA.

  2. Networking Events: You can attend networking events and conferences that are specifically targeted for entrepreneurs to meet investors. There are now plenty of events happening both offline and virtually, which you can find through Meetup.com.

  3. Incubator or Accelerator Program: Many incubator and accelerator programs offer access to their network of investors which will assist you with introductions to angel investors.

  4. Referrals: If you have a community of entrepreneurs, industry colleagues, and other business networks, do leverage their relationships to potential angel investors and ask for their contacts.

  5. Direct Outreach: You may scout through LinkedIn to find potential angel investors and contact them directly via email or organize a meeting.


Keep in mind that angel investors tend to invest in areas of their expertise, so make sure that the investors you're approaching are a suitable fit for your business and have a track record of investing in comparable businesses.





Angel Investment Networks in the United States of America



  • Stage: Seed

  • Focus: Sector Agnostic

  • Year of Inception: -

  • Notable Portfolio: -

  • Location: USA-wide



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: -

  • Notable Portfolio: -

  • Location: USA-wide



  • Stage: Pre Seed, Seed

  • Focus: Sector Agnostic

  • Year of Inception: 2012

  • Notable Portfolio: Automotus, Page Vault, Rentlytics, Vapogenix

  • Location: Chicago



  • Stage: Pre Seed, Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2001

  • Notable Portfolio: Galen Data, SipNShut, Hoth Intelligence

  • Location: Texas



  • Stage: Pre Seed, Seed, Series A

  • Focus: Technology

  • Year of Inception: 2013

  • Notable Portfolio: Chattr, Clientbook, Peerfit, Stylust

  • Location: Florida





  • Stage: Seed

  • Focus: Information Technology, Life Science

  • Year of Inception: 2007

  • Notable Portfolio: Carmell Therapeutics, Airship, Strongwatch, Lawlytics

  • Location: Arizona



  • Stage: Seed

  • Focus: Sector Agnostic

  • Year of Inception: 2017

  • Notable Portfolio: MySet, Wispr Systems, Glo Cubes

  • Location: Alabama



  • Stage: Seed

  • Focus: Sector Agnostic, Female Founders

  • Year of Inception: 1999

  • Notable Portfolio: SoapBox, Amp.it, Repurpose, Poshly, PrecisionLife

  • Location: California



  • Stage: Seed

  • Focus: Technology, Internet, New Media, Healthcare and Medical Devices, Packaged Consumer Goods

  • Year of Inception: 2004

  • Notable Portfolio: Krilix, Eye-com, Unicon Systems, NX Pharmagen

  • Location: California



  • Stage: Seed

  • Focus: Technology, Life Science

  • Year of Inception: 1994

  • Notable Portfolio: HealthCrowd, Sherpa, Shazam, Neofroma

  • Location: California





  • Stage: Seed, Series A

  • Focus: B2B SaaS, Enterprise Software, FinTech, Digital Media, Medtech, Biotech, AgriFoodTech, Consumer Products

  • Year of Inception: 2000

  • Notable Portfolio: Tenacity, SuperWorld

  • Location: California



  • Stage: Seed, Series A

  • Focus: Consumer Products & Services, Food & Beverage, Healthcare, Industrial Internet, Mobile & Telecom, Software, FinTech, Logistics, Security

  • Year of Inception: 2006

  • Notable Portfolio: Avisa, Candidly, Loku, Pinwheel, Vertify

  • Location: Texas



  • Stage: Seed, Series A

  • Focus: Hard Technology

  • Year of Inception: 2011

  • Notable Portfolio: Zylo, Synode Systems, Pediatric Bioscience

  • Location: California



  • Stage: Seed, Series A

  • Focus: Impact

  • Year of Inception: 2015

  • Notable Portfolio: ResilientGrid, FlowBelow, Querium, Bodhi

  • Location: Texas



  • Stage: Seed, Series A

  • Focus: Life Science

  • Year of Inception: 2005

  • Notable Portfolio: Allylix, Carmenta, Advanced Cardiac Therapeutics, Spirox

  • Location: California







  • Stage: Seed, Series A

  • Focus: Life Science

  • Year of Inception: 2012

  • Notable Portfolio: PainQX, Elysium Therapeutics, Sana Health

  • Location: New York



  • Stage: Seed, Series A

  • Focus: Medical Diagnostics or Biopharma, Medical Devices, Non Life Science Products / Services

  • Year of Inception: 2016

  • Notable Portfolio: Arctx, Vitrivax, Lindy Biosciences, Gemelli Biotech

  • Location: North Carolina



  • Stage: Seed, Series A

  • Focus: Science and Technology

  • Year of Inception: 2000

  • Notable Portfolio: Circa, RevenueBase, Pixability, Netra

  • Location: Massachusetts



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2000

  • Notable Portfolio: -

  • Location: USA-wide chapters



  • Stage: Seed

  • Focus: Sector Agnostic

  • Year of Inception: 2004

  • Notable Portfolio: Crimson Hexagon, SeamlessDocs, Crowdly, AdStash

  • Location: New York






  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 1997

  • Notable Portfolio: Abintus Bio, Beacon Healthcare, GrandPad, Green Dot, Eyedaptic

  • Location: California



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 1997

  • Notable Portfolio: Clarisonic, DocuSign, Kaskada, SoundCommerce

  • Location: Washington



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2003

  • Notable Portfolio: NuvOx Pharma, VuPulse, Admiral, Aegle Therapeutics

  • Location: Florida



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2008

  • Notable Portfolio: Lula, Consensus, RealVu, Symptom.ly

  • Location: Utah



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2014

  • Notable Portfolio: AmplifiedAg, Cure Mint, HopDrive, Zylo

  • Location: South Carolina





  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2014

  • Notable Portfolio: CoreBiome, JoiaSpirit, Nomi, StemoniX

  • Location: Minnesota



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2015

  • Notable Portfolio: Brandefy, Cerillo, Karios, The Shed, Lumin

  • Location: Virginia



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2005

  • Notable Portfolio: Ideate Medical, Aptimmune, Advocado

  • Location: Missouri



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2003

  • Notable Portfolio: Abogen, Amplify, Cerahelix, Groupize

  • Location: Maine



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2008

  • Notable Portfolio: Abilitech, BrainCheck, Immerse, StreamVine, Vartega

  • Location: Texas





  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2005

  • Notable Portfolio: Elevate K-12, Lumencor, Healionics

  • Location: Washington



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2009

  • Notable Portfolio: Gearbox Express, Personify, Serionix, SNOOZ

  • Location: Illinois



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2011

  • Notable Portfolio: Genomenon, Akadeum Life Sciences

  • Location: Michigan



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2006

  • Notable Portfolio: BenefitBay, Alpaca, Elevator

  • Location: Nebraska



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2014

  • Notable Portfolio: Tympanogen, Altis Biosystems, Ash & Erie

  • Location: Louisiana





  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2012

  • Notable Portfolio: Bedrock Data, CampusSIMS, Mobee, Diesel Labs

  • Location: Massachusetts



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 1997

  • Notable Portfolio: Crytica Security, Membrion

  • Location: Nevada



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2011

  • Notable Portfolio: FitBark, MeetCaregivers

  • Location: Massachusetts



  • Stage: Seed, Series A

  • Focus: Sector Agnostic, Female Founders

  • Year of Inception: 2005

  • Notable Portfolio: Joylux, Nalu, Zenflow, Design2Launch, Amplyx

  • Location: New York



  • Stage: Seed, Series A

  • Focus: Sector Agnostic

  • Year of Inception: 2017

  • Notable Portfolio: VuPulse, Knack Tutoring, KinoTek, TSOLife

  • Location: Florida





  • Stage: Seed, Series A

  • Focus: Sector Agnostic, SaaS

  • Year of Inception: 2000

  • Notable Portfolio: Xeal, SpineAlign, Alleyoop, UNest, Basepaws

  • Location: California



  • Stage: Seed, Series A

  • Focus: Sector Agnostic, Trans women, cis women, nonbinary, two-spirit, agender, and gender-nonconforming founders

  • Year of Inception: 2011

  • Notable Portfolio: Invio, NeuroVice, Repurpose, Wave Therapeutics

  • Location: Texas



  • Stage: Seed, Series A

  • Focus: Social Impact

  • Year of Inception: 2015

  • Notable Portfolio: Connxus, Motivo, Otosense, New Wave, Livwell

  • Location: Colorado



  • Stage: Seed, Series A

  • Focus: Software/Healthcare, IT, Life Sciences, Hard Tech, Consumer

  • Year of Inception: 1999

  • Notable Portfolio: Quartile, WizeHive, Monetate, Synova Healthcare

  • Location: Pennsylvania



  • Stage: Seed, Series A

  • Focus: Sports

  • Year of Inception: 2017

  • Notable Portfolio: Oddlot, Heroclip, Alleviate, Pledge It

  • Location: Oregon





  • Stage: Seed, Series A

  • Focus: Technology

  • Year of Inception: 2000

  • Notable Portfolio: CloudCath, Membrion, Kiana Analytics, Orbit Fab

  • Location: California



  • Stage: Seed, Series A

  • Focus: Technology

  • Year of Inception: 2013

  • Notable Portfolio: Sempli, Revibe, First,io

  • Location: North Carolina



  • Stage: Seed, Series A

  • Focus: Technology

  • Year of Inception: 2003

  • Notable Portfolio: 4Moms, Anglr, Cognition Therapeutics, C360 Live

  • Location: Pennsylvania



  • Stage: Seed, Series A

  • Focus: Technology

  • Year of Inception: 1998

  • Notable Portfolio: CodeGuard, YellowCard, Clockwise.MD, Predikto

  • Location: Georgia



  • Stage: Seed, Series A

  • Focus: Technology

  • Year of Inception: 2006

  • Notable Portfolio: CurvaFix, Pyx Health, Vartega, Materna Medical

  • Location: Montana



  • Stage: Seed, Series A

  • Focus: Technology, Advanced Materials, Life Sciences, IT

  • Year of Inception: 2000

  • Notable Portfolio: Airway Therapeutics, Endosphere, Cladwell

  • Location: Ohio





Closing Thoughts on Angel Investment Networks in the United States of America


Angel investment networks may be an excellent source of funding for American entrepreneurs. These networks can provide access to funding or individual investors, as well as mentorship and other key contacts. However, it's also important to note that it is not the only choice. Depending on the startup's specific needs and circumstances, other funding options such as venture capital, crowdsourcing, and regular bank loans may be worth pursuing.


Overall, having a clear grasp of your startup's financial requirements and goals is critical to knowing whether angel investments are a right fit for you, and having a great business strategy and a captivating pitch will help you to succeed in securing funding from the right angel investors.




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